High Resolution EPR

Filename: high-resolution-epr.pdf
ISBN: 038784855X
Release Date: 2009-06-29
Number of pages: 666
Author: Graeme Hanson
Publisher: Springer

Download and read online High Resolution EPR in PDF and EPUB Metalloproteins comprise approximately 30% of all known proteins, and are involved in a variety of biologically important processes, including oxygen transport, biosynthesis, electron transfer, biodegradation, drug metabolism, proteolysis, and hydrolysis of amides and esters, environmental sulfur and nitrogen cycles, and disease mechanisms. EPR spectroscopy has an important role in not only the geometric structural characterization of the redox cofactors in metalloproteins but also their electronic structure, as this is crucial for their reactivity. The advent of x-ray crystallographic snapshots of the active site redox cofactors in metalloenzymes in conjunction with high-resolution EPR spectroscopy has provided detailed structural insights into their catalytic mechanisms. This volume was conceived in 2005 at the Rocky Mountain Conference on Analytical Chemistry (EPR Symposium) to highlight the importance of high-resolution EPR spectroscopy to the structural (geometric and electronic) characterization of redox active cofactors in metalloproteins. We have been fortunate to have enlisted internationally recognized experts in this joint venture to provide the scientific community with an overview of high-resolution EPR and its application to metals in biology. This volume, High-Resolution EPR: Applications to Metalloenzymes and Metals in Medicine, covers high-resolution EPR methods, iron proteins, nickel and copper enzymes, and metals in medicine. An eloquent synopsis of each chapter is provided by John Pilbrow in the Introduction. A second volume, Metals in Biology: Applications of High-Resolution EPR to Metalloenzymes, will appear later this year covering the complement of other metalloproteins. One of the pioneers in the development of pulsed EPR and its application to metalloproteins was Arthur Schweiger, whose contribution we include in this volume. Unfortunately, he passed away suddenly during the preparation of this volume. The editors and coauthors are extremely honored to dedicate this volume to the memory of Arthur Schweiger in recognition of his technical advances and insights into pulsed EPR and its application to metalloproteins. Arthur was extremely humble and treated everyone with equal respect. He was a gifted educator with an ability to explain complex phenomena in terms of simple intuitive pictures, had a delightful personality, and continues to be sadly missed by the community. It is an honor for the editors to facilitate the dissemination of these excellent contributions to the scientific community. Suggestions for future volumes are always appreciated.


Structure and Function

Filename: structure-and-function.pdf
ISBN: 9048128889
Release Date: 2009-12-02
Number of pages: 260
Author: Peter Comba
Publisher: Springer Science & Business Media

Download and read online Structure and Function in PDF and EPUB The art of chemistry is to thoroughly understand the properties of molecular compounds and materials and to be able to prepare novel compounds with p- dicted and desirable properties. The basis for progress is to fully appreciate and fundamentally understand the intimate relation between structure and function. The thermodynamic properties (stability, selectivity, redox potential), reactivities (bond breaking and formation, catalysis, electron transfer) and electronic properties (spectroscopy, magnetism) depend on the structure of a compound. Nevertheless, the discovery of novel molecular compounds and materials with exciting prop- ties is often and to a large extent based on serendipity. For compounds with novel and exciting properties, a thorough analysis of experimental data – state-of-the-art spectroscopy, magnetism, thermodynamic properties and/or detailed mechanistic information – combined with sophisticated electronic structure calculations is p- formed to interpret the results and fully understand the structure, properties and their interrelation. From these analyses, new models and theories may emerge, and this has led to the development of ef cient models for the design and interpre- tion of new materials and important new experiments. The chapters in this book therefore describe various fundamental aspects of structures, dynamics and physics of molecules and materials. The approaches, data and models discussed include new theoretical developments, computational studies and experimental work from molecular chemistry to biology and materials science.


Future Directions in Metalloprotein and Metalloenzyme Research

Filename: future-directions-in-metalloprotein-and-metalloenzyme-research.pdf
ISBN: 9783319591001
Release Date: 2017-09-13
Number of pages: 191
Author: Graeme Hanson
Publisher: Springer

Download and read online Future Directions in Metalloprotein and Metalloenzyme Research in PDF and EPUB This book covers the latest developments in metalloenzymes, including characterizing metal bridging in proteins and peptides, copper(II) complexes of marine peptides, high-spin Co(II) in model and metalloprotein systems to enzymes such as the molybdenum-containing enzymes, CW and pulse EPR of cytochrome P450 enzymes and the radical S-adenosylmethionine FeS family. In the previous two related volumes in the Biological Magnetic Resonance series, High-Resolution EPR: Applications to Metalloenzymes and Metals in Medicine and Metals in Biology:Applications of High-Resolution EPR to Metalloenzymes, topics covered included high-resolution EPR methods, iron proteins, nickel and copper enzymes, metals in medicine, iron–sulfur cluster-containing proteins, and molybdenum enzymes. In this volume, new developments in these areas are covered in detail and new areas that have emerged are also detailed. This is an ideal book for graduate students and researchers working in the fie lds of high-resolution EPR, metalloenzymes, and metals in biology.


Metals in Biology

Filename: metals-in-biology.pdf
ISBN: 1461424968
Release Date: 2012-02-25
Number of pages: 419
Author: Graeme Hanson
Publisher: Springer

Download and read online Metals in Biology in PDF and EPUB Metal ions in biology is an ever expanding area in science and medicine involving metal ions in proteins and enzymes, their biosynthesis, catalysis, electron transfer, metal ion trafficking, gene regulation and disease. While X-ray crystallography has provided snapshots of the geometric structures of the active site redox cofactors in these proteins, the application of high resolution EPR spectroscopy in conjunction with quantum chemistry calculations has enabled, in many cases, a detailed understanding of a metalloenzymes mechanism through investigations of the geometric and electronic structure of the resting, enzyme-substrate intermediates and product complexes. This volume, Part II of a two-volume set demonstrates the application of high resolution EPR spectroscopy in determining the geometric and electronic structure of active site metal ion centers in iron sulfur cluster containing metalloproteins, mononuclear molybdenum metalloenzymes, manganese-containing enzymes and novel metalloproteins.


High Resolution EPR

Filename: high-resolution-epr.pdf
ISBN: 9780387848563
Release Date: 2009-06-19
Number of pages: 666
Author: Graeme Hanson
Publisher: Springer Science & Business Media

Download and read online High Resolution EPR in PDF and EPUB Metalloproteins comprise approximately 30% of all known proteins, and are involved in a variety of biologically important processes, including oxygen transport, biosynthesis, electron transfer, biodegradation, drug metabolism, proteolysis, and hydrolysis of amides and esters, environmental sulfur and nitrogen cycles, and disease mechanisms. EPR spectroscopy has an important role in not only the geometric structural characterization of the redox cofactors in metalloproteins but also their electronic structure, as this is crucial for their reactivity. The advent of x-ray crystallographic snapshots of the active site redox cofactors in metalloenzymes in conjunction with high-resolution EPR spectroscopy has provided detailed structural insights into their catalytic mechanisms. This volume was conceived in 2005 at the Rocky Mountain Conference on Analytical Chemistry (EPR Symposium) to highlight the importance of high-resolution EPR spectroscopy to the structural (geometric and electronic) characterization of redox active cofactors in metalloproteins. We have been fortunate to have enlisted internationally recognized experts in this joint venture to provide the scientific community with an overview of high-resolution EPR and its application to metals in biology. This volume, High-Resolution EPR: Applications to Metalloenzymes and Metals in Medicine, covers high-resolution EPR methods, iron proteins, nickel and copper enzymes, and metals in medicine. An eloquent synopsis of each chapter is provided by John Pilbrow in the Introduction. A second volume, Metals in Biology: Applications of High-Resolution EPR to Metalloenzymes, will appear later this year covering the complement of other metalloproteins. One of the pioneers in the development of pulsed EPR and its application to metalloproteins was Arthur Schweiger, whose contribution we include in this volume. Unfortunately, he passed away suddenly during the preparation of this volume. The editors and coauthors are extremely honored to dedicate this volume to the memory of Arthur Schweiger in recognition of his technical advances and insights into pulsed EPR and its application to metalloproteins. Arthur was extremely humble and treated everyone with equal respect. He was a gifted educator with an ability to explain complex phenomena in terms of simple intuitive pictures, had a delightful personality, and continues to be sadly missed by the community. It is an honor for the editors to facilitate the dissemination of these excellent contributions to the scientific community. Suggestions for future volumes are always appreciated.


EPR of Free Radicals in Solids I

Filename: epr-of-free-radicals-in-solids-i.pdf
ISBN: 9789400748934
Release Date: 2012-12-12
Number of pages: 414
Author: Anders Lund
Publisher: Springer Science & Business Media

Download and read online EPR of Free Radicals in Solids I in PDF and EPUB EPR of Free Radicals in Solids: Trends in Methods and Applications, 2nd ed. presents a critical two volume review of the methods and applications of EPR (ESR) for the study of free radical processes in solids. Emphasis is on the progress made in the developments in EPR technology, in the application of sophisticated matrix isolation techniques and in the advancement in quantitative EPR that have occurred since the 1st edition was published. Improvements have been made also at theoretical level, with the development of methods based on first principles and their application to the calculation of magnetic properties as well as in spectral simulations. EPR of Free Radicals in Solids I focuses on the trends in experimental and theoretical methods to extract structural and dynamical properties of radicals and spin probes in solid matrices by continuous wave (CW) and pulsed techniques. It presents simulation techniques and software for CW and pulsed EPR as well as studies of quantum effects at low temperature. The chapters dealing with quantum chemistry methods for the theoretical interpretation of hyperfine coupling tensors and g-tensors have been much extended in this edition and a new chapter on the calculation of zero-field splitting tensors has been added. This new edition is a valuable resource to experimentalists and theoreticians in research involving free radicals, as well as for students of advanced courses in physical chemistry, chemical physics, materials science, biophysics, biochemistry and related fields. This new edition is a valuable resource to experimentalists and theoreticians in research involving free radicals, as well as for students of advanced courses in physical chemistry, chemical physics, materials science, biophysics, biochemistry and related fields.


Advances in Carbohydrate Chemistry and Biochemistry

Filename: advances-in-carbohydrate-chemistry-and-biochemistry.pdf
ISBN: 9780123855183
Release Date: 2011-12
Number of pages: 328
Author: Derek Horton
Publisher: Academic Press

Download and read online Advances in Carbohydrate Chemistry and Biochemistry in PDF and EPUB Since its inception in 1945, this serial has provided critical and integrating articles written by research specialists that bring together industrial, analytical and technological aspects of biochemistry, organic chemistry and instrumentation methodology in the study of carbohydrates. The articles provide a definitive interpretation of the current status and future trends in carbohydrate chemistry and biochemistry. Features contributions from leading authorities and industry experts Informs and updates on all the latest developments in the field


Spectroscopic and theoretical studies of oxygen intermediates and catalytic O2 reduction in the multicopper oxidases

Filename: spectroscopic-and-theoretical-studies-of-oxygen-intermediates-and-catalytic-o2-reduction-in-the-multicopper-oxidases.pdf
ISBN: STANFORD:36105128072977
Release Date: 2007
Number of pages: 476
Author: Jungjoo Yoon
Publisher:

Download and read online Spectroscopic and theoretical studies of oxygen intermediates and catalytic O2 reduction in the multicopper oxidases in PDF and EPUB


Metal Ions in Biology and Medicine

Filename: metal-ions-in-biology-and-medicine.pdf
ISBN: 2742001301
Release Date: 1996
Number of pages: 703
Author: Philippe Collery
Publisher: John Libbey Eurotext

Download and read online Metal Ions in Biology and Medicine in PDF and EPUB


Wiley encyclopedia of chemical biology

Filename: wiley-encyclopedia-of-chemical-biology.pdf
ISBN: 0471754773
Release Date: 2009
Number of pages:
Author: Tadhg P. Begley
Publisher:

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The British National Bibliography

Filename: the-british-national-bibliography.pdf
ISBN: STANFORD:36105211722686
Release Date: 2009
Number of pages:
Author: Arthur James Wells
Publisher:

Download and read online The British National Bibliography in PDF and EPUB


Separated Isotopes

Filename: separated-isotopes.pdf
ISBN: NAP:12880
Release Date: 1982
Number of pages: 279
Author:
Publisher: National Academies

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Magnetic resonance

Filename: magnetic-resonance.pdf
ISBN: CHI:58091540
Release Date: 1999
Number of pages: 161
Author: P. T. Manoharan
Publisher:

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Bulletin of Magnetic Resonance

Filename: bulletin-of-magnetic-resonance.pdf
ISBN: UIUC:30112028882386
Release Date: 1992
Number of pages:
Author:
Publisher:

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